Article
Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia: its impact on the performance of malaria rapid diagnostic tests.
Malaria journal - 9 Oct 2021
Alemayehu Gezahegn Solomon, Messele Alebachew, Blackburn Kayla, Lopez Karen, Lo Eugenia, Janies Daniel, Golassa Lemu
Abstract excerpt
BACKGROUND: Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp2/3) threaten existing malaria case management and control efforts. The main objective of this study was to investigate the genetic variations of the pfhrp2/3 genes....
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