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Article

Sequence variation in Plasmodium falciparum Histidine Rich Proteins 2 and 3 in Indian isolates: Implications for Malaria Rapid Diagnostic Test Performance.

Scientific reports - 2 May 2017

Kumar Bharti Praveen, Singh Chandel Himanshu, Krishna Sri, Nema Shrikant, Ahmad Amreen, Udhayakumar Venkatachalam, Singh Neeru

Abstract excerpt

Commercial malaria rapid diagnostic tests (RDTs) detect P. falciparum histidine rich protein 2 (PfHRP2) and cross react with PfHRP3, a structural homologue. Here, we analysed natural variations in PfHRP2 and PfHRP3 sequences from Indian isolates and correlated these variations with RDT reactivity. A total 1392 P. falciparum positive samples collected from eight endemic states were PCR amplified for Pfhrp2 and...

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Identifiers

PMID: 28465622
DOI: 10.1038/s41598-017-01506-9
PMCID: PMC5430971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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