Back to search

Article

Extensive Deletion and Sequence Variation of Plasmodium Falciparum Histidine Rich Protein 2/3 (pfhrp2/3) Genes in Ethiopia: Implication for RDT-based Malaria Diagnosis and Control

2020-04-15

Abstract excerpt

<title>Abstract</title> <p>Background: Despite remarkable malaria reduction in recent years, malaria remains a public health problem in Ethiopia. With the introduction of rapid diagnostic tests (RDTs), malaria diagnosis has been transformed. However, the Plasmodium falciparum histidine rich protein 2 ( hrp 2) that is targeted by the most widely used RDTs is prone to genetic mutations and gene deletions as observe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4c18e3be-0339-50b9-9fa8-429e9b7cc5b5
DOI
10.21203/rs.3.rs-22606/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Extensive Deletion and Sequence Variation of Plasmodium Falciparum Histidine Rich Protein 2/3 (pfhrp2/3) Genes in Ethiopia: Implication for RDT-based Malaria Diagnosis and ControlDOI 10.21203/rs.3.rs-22606/v1
Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosisSemantic proximity
High prevalence and extended deletions in Plasmodium falciparum hrp2/3 genomic loci in EthiopiaSemantic proximity
High prevalence of pfhrp2 and pfhrp3 gene deletions and major threat to malaria control programs in EthiopiaSemantic proximity
Genetic Variations of Plasmodium Falciparum Histidine-rich Protein 2 and 3 in Assosa Zone, Ethiopia: Its Impact on the Performance of Malaria Rapid Diagnostic TestsSemantic proximity
Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions and Their Implications in Malaria ControlSemantic proximity
Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions in Strains from Nigeria, Sudan, and South SudanSemantic proximity
Prevalence of Plasmodium falciparum Isolates Lacking the Histidine Rich Protein 2 Gene Among Symptomatic Malaria Patients in Kwilu Province, DR. Congo.Semantic proximity
Emergence and evolution of <i>Plasmodium falciparum</i> histidine-rich protein 2 and 3 deletion mutant parasites in EthiopiaSemantic proximity
Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, EthiopiaSemantic proximity
Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia: its impact on the performance of malaria rapid diagnostic tests.Semantic proximity
Deletion of target gene (histidine-rich protein 2/3) for Plasmodium falciparum rapid diagnostic tests in Amhara region, Ethiopia: a cross-sectional studySemantic proximity
Deletions of the Plasmodium falciparum pfhrp2 and pfhrp3 genes among patients enrolled at six locations in the DRC: 2017–2018Semantic proximity
Select a neighboring publication to make it the new centre.