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Article

Genetic variation in histidine rich proteins among Indian Plasmodium falciparum population: possible cause of variable sensitivity of malaria rapid diagnostic tests.

Malaria journal - 28 Aug 2012

Kumar Navin, Singh Jai Pn, Pande Veena, Mishra Neelima, Srivastava Bina, Kapoor Ridhima, Valecha Neena, Anvikar Anupkumar R

Abstract excerpt

BACKGROUND: Rapid diagnostic tests (RDTs) have revolutionized the diagnosis of malaria. Among the various factors affecting RDTs sensitivity is genetic variation of the antigen used. The genetic variation in PfHRP2 and PfHRP3 proteins was studied among the Indian Plasmodium falciparum isolates. METHODS: One hundred and forty isolates of P. falciparum were collected from six geographical regions of India. Target...

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Identifiers

PMID: 22929537
DOI: 10.1186/1475-2875-11-298
PMCID: PMC3475030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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