Article
Network propagation-based prioritization of long tail genes in 17 cancer types.
Genome biology - 7 Oct 2021
Mohsen Hussein, Gunasekharan Vignesh, Qing Tao, Seay Montrell, Surovtseva Yulia, Negahban Sahand, Szallasi Zoltan, Pusztai Lajos, Gerstein Mark B
Abstract excerpt
BACKGROUND: The diversity of genomic alterations in cancer poses challenges to fully understanding the etiologies of the disease. Recent interest in infrequent mutations, in genes that reside in the "long tail" of the mutational distribution, uncovered new genes with significant implications in cancer development. The study of cancer-relevant genes often requires integrative approaches pooling together multiple...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.