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Article

Wavelet Screening: a novel approach to analyzing GWAS data.

BMC bioinformatics - 7 Oct 2021

Denault William R P, Gjessing Håkon K, Juodakis Julius, Jacobsson Bo, Jugessur Astanand

Abstract excerpt

BACKGROUND: Traditional methods for single-variant genome-wide association study (GWAS) incur a substantial multiple-testing burden because of the need to test for associations with a vast number of single-nucleotide polymorphisms (SNPs) simultaneously. Further, by ignoring more complex joint effects of nearby SNPs within a given region, these methods fail to consider the genomic context of an association with...

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PMID: 34620077
DOI: 10.1186/s12859-021-04356-5
PMCID: PMC8499521

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