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Article

Genetic capitalism and stabilizing selection of antimicrobial resistance genotypes in Escherichia coli.

Cladistics : the international journal of the Willi Hennig Society - 1 Aug 2020

Ford Colby T, Zenarosa Gabriel Lopez, Smith Kevin B, Brown David C, Williams John, Janies Daniel

Abstract excerpt

Antimicrobial resistance (AMR) in pathogenic strains of bacteria, such as Escherichia coli (E. coli), adversely impacts personal and public health. In this study, we examine competing hypotheses for the evolution of AMR including (i) 'genetic capitalism' in which genotypes that confer antibiotic resistance are gained and not often lost in lineages, and (ii) 'stabilizing selection' in which genotypes that confer...

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PMID: 34618971
DOI: 10.1111/cla.12421

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