Article

Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics

2025-01-16

Abstract excerpt

Antibiotic resistance is frequently observed shortly after the clinical introduction of an antibiotic. Whether and how frequently that resistance occurred before the introduction is harder to determine, as isolates could not have been tested for resistance before an antibiotic was discovered. Historical collections, like the British National Collection of Type Cultures (NCTC), stretching back to 1885, provide a wi...

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Literature Corpus work: 1adadcca-74ce-579e-80f1-b649eaf29d8d
DOI: 10.1101/2025.01.16.633422

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