Article
Disease-Associated Risk Variants in ANRIL Are Associated with Tumor-Infiltrating Lymphocyte Presence in Primary Melanomas in the Population-Based GEM Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2021
Davari Danielle R, Orlow Irene, Kanetsky Peter A, Luo Li, Edmiston Sharon N, Conway Kathleen, Parrish Eloise A, Hao Honglin, Busam Klaus J, Sharma Ajay, Kricker Anne, Cust Anne E, Anton-Culver Hoda, Gruber Stephen B, Gallagher Richard P, Zanetti Roberto, Rosso Stefano, Sacchetto Lidia, Dwyer Terence, Ollila David W, Begg Colin B, Berwick Marianne, Thomas Nancy E
Abstract excerpt
BACKGROUND: Genome-wide association studies have reported that genetic variation at ANRIL (CDKN2B-AS1) is associated with risk of several chronic diseases including coronary artery disease, coronary artery calcification, myocardial infarction, and type 2 diabetes mellitus. ANRIL is located at the CDKN2A/B locus, which encodes multiple melanoma tumor suppressors. We investigated the association of these variants...
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