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Article

Inherited genetic variants associated with occurrence of multiple primary melanoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2015

Gibbs David C, Orlow Irene, Kanetsky Peter A, Luo Li, Kricker Anne, Armstrong Bruce K, Anton-Culver Hoda, Gruber Stephen B, Marrett Loraine D, Gallagher Richard P, Zanetti Roberto, Rosso Stefano, Dwyer Terence, Sharma Ajay, La Pilla Emily, From Lynn, Busam Klaus J, Cust Anne E, Ollila David W, Begg Colin B, Berwick Marianne, Thomas Nancy E

Abstract excerpt

Recent studies, including genome-wide association studies, have identified several putative low-penetrance susceptibility loci for melanoma. We sought to determine their generalizability to genetic predisposition for multiple primary melanoma in the international population-based Genes, Environment, and Melanoma (GEM) Study. GEM is a case-control study of 1,206 incident cases of multiple primary melanoma and...

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Identifiers

PMID: 25837821
DOI: 10.1158/1055-9965.EPI-14-1426
PMCID: PMC4452425

Genes

GEM
MTAP
NCOA6
TERT
TYR
TYRP1
PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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