Article
Evaluation of KIR genes in recurrent miscarriage.
Journal of assisted reproduction and genetics - 1 Sept 2012
Ozturk Ozlem Goruroglu, Sahın Gulhan, Karacor Esin Damla Zıyanoglu, Kucukgoz Umran
Abstract excerpt
PURPOSE: Natural killer (NK) cells express killer immunoglobulin-like receptors (KIRs) which recognize HLA class I molecules on trophoblasts. KIRs could either activate NK cells or inhibit them to produce soluble factors necessary for the maintenance of pregnancy, thus they are suspected of being involved in the causes of recurrent miscarriage. The aim of this study was to evaluate whether there is any possible...
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