Article
The Roles of Uterine Natural Killer (NK) Cells and KIR/HLA-C Combination in the Development of Preeclampsia: A Systematic Review.
BioMed research international - 1 Jan 2020
Yang Xiuhua, Yang Yahui, Yuan Yiru, Liu Lin, Meng Tao
Abstract excerpt
Preeclampsia (PE) is termed as a systemic disease that involves multiple organs; however, the exact etiology is still quite unclear. It is believed that the poor remodeling of uterine spiral arteries triggers PE, thereby causing failed placentation and producing inflammatory factors. The decline of blood flow results in lowering the nutrients and oxygen received by the fetus and augmenting the placental pressure...
Topics
- Animals
- Female
- Fetus
- Genotype
- HLA-C Antigens
- Humans
- Killer Cells, Natural
- Pre-Eclampsia
- Pregnancy
- Receptors, KIR
- Trophoblasts
- Uterine Artery