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Article

Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression.

Frontiers in immunology - 1 Jan 2021

Wilson Andrew, Shakhtour Leyn, Ward Adam, Ren Yanqin, Recarey Melina, Stevenson Eva, Korom Maria, Kovacs Colin, Benko Erika, Jones R Brad, Lynch Rebecca M

Abstract excerpt

Although antiretroviral therapy (ART) successfully suppresses HIV-1 replication, ART-treated individuals must maintain therapy to avoid rebound from an integrated viral reservoir. Strategies to limit or clear this reservoir are urgently needed. Individuals infected for longer periods prior to ART appear to harbor more genetically diverse virus, but the roles of duration of infection and viral diversity in the...

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Share to Anti-Retroviral Agents
Share to Broadly Neutralizing Antibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to env Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 34603284
DOI: 10.3389/fimmu.2021.710327
PMCID: PMC8479156

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