Article
Human immunodeficiency virus type 1 variants isolated from single plasma samples display a wide spectrum of neutralization sensitivity.
Journal of virology - 1 Sept 2005
Skrabal Katharina, Saragosti Sentob, Labernardière Jean-Louis, Barin Francis, Clavel François, Mammano Fabrizio
Abstract excerpt
Individuals infected with human immunodeficiency virus type 1 (HIV-1) harbor a mixture of viral variants with different sequences and in some instances with different phenotypic properties. Major and rapid fluctuations in the proportion of viral variants coexisting in an infected individual can be observed under strong pharmacological and immune selective pressure. Because of the short half-life of HIV-infected...
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