Article
Effect of Apolipoprotein E4 on the Driving Behavior of Patients with Amnestic Mild Cognitive Impairment or Mild Alzheimer's Disease Dementia.
Journal of Alzheimer's disease : JAD - 1 Jan 2021
Stanitsa Evangelia, Economou Alexandra, Beratis Ion, Kontaxopoulou Dionysia, Fragkiadaki Stella, Papastefanopoulou Vicky, Pavlou Dimosthenis, Papantoniou Panagiotis, Kroupis Christos, Papatriantafyllou John, Stefanis Leonidas, Yannis George, Papageorgiou Sokratis G
Abstract excerpt
BACKGROUND: The driving behavior of patients with mild Alzheimer's disease dementia (ADD) and patients with mild cognitive impairment (MCI) is frequently characterized by errors. A genetic factor affecting cognition is apolipoprotein E4 (APOE4), with carriers of APOE4 showing greater episodic memory impairment than non-carriers. However, differences in the driving performance of the two groups have not been...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Amnesia
- Apolipoprotein E4
- Automobile Driving
- Cognition
- Cognitive Dysfunction
- Computer Simulation
- Genotype
- Humans
- Middle Aged