Article
Prostate cancer genetic propensity risk score may modify the association between this tumour and type 2 diabetes mellitus (MCC-Spain study).
Prostate cancer and prostatic diseases - 1 Apr 2022
Barrios-Rodríguez Rocío, García-Esquinas Esther, Pérez-Gómez Beatriz, Castaño-Vinyals Gemma, Llorca Javier, de Larrea-Baz Nerea Fernández, Olmedo-Requena Rocío, Vanaclocha-Espi Mercedes, Alguacil Juan, Fernández-Tardón Guillermo, Fernández-Navarro Pablo, Cecchini Lluís, Lope Virginia, Gómez-Acebo Inés, Aragonés Nuria, Kogevinas Manolis, Pollán Marina, Jiménez-Moleón José Juan
Abstract excerpt
BACKGROUND: Some studies have reported an inverse association between type 2 diabetes mellitus (T2DM) and prostate cancer (PCa), but results on this issue are still inconsistent. In this study, we evaluate whether this heterogeneity might be related to differences in this relationship by tumour or by individual genetic susceptibility to PCa. METHODS: We studied 1047 incident PCa cases and 1379 randomly selected...
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