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BRCA1 and VDR gene polymorphisms are associated with prostate cancer risk in Mexican men.

Molecular carcinogenesis - 1 Jun 2020

Martínez-Nava Gabriela Angélica, Gómez Rocío, Burguete-García Ana Isabel, Vázquez-Salas Ruth Argelia, Ventura-Bahena Arianna, Torres-Sánchez Luisa

Abstract excerpt

Prostate cancer (PC) is a polygenic disease with broad differences across ethnicities. BRCA1/2 and VDR have exhibited a featured genetic contribution to PC development in European populations. Nonetheless, its contribution in Latino populations specifically among Mexican men, where 70% of PC cases are detected in advanced stages, is still unknown. The contribution of seven polymorphisms in BRCA1/2 and VDR genes...

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PMID: 32219892
DOI: 10.1002/mc.23187

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