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Identification of dysregulated genes and pathways of different brain regions in Alzheimer’s disease

5 Feb 2020

Abstract excerpt

Background: Alzheimer’s disease (AD) is a degenerative neurologic disease. The study aimed to identify the key differentially expressed genes (DEGs) and pathways in AD pathogenesis and obtain potential biomarkers in AD diagnosis.Methods: An integrated analysis of publicly available Gene Expression Omnibus datasets of AD was performed. DEGs in hippocampus tissue (HIP), temporal gyrus tissue (TG), frontal gyrus...

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PMID: 32019384
DOI: 10.1080/00207454.2020.1720677

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