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Article

Chronic Porphyromonas gingivalis lipopolysaccharide induces adverse myocardial infarction wound healing through activation of CD8+ T cells.

American journal of physiology. Heart and circulatory physiology - 1 Nov 2021

Zaidi Yusra, Corker Alexa, Vasileva Valeriia Y, Oviedo Kimberly, Graham Connor, Wilson Kyrie, Martino John, Troncoso Miguel, Broughton Philip, Ilatovskaya Daria V, Lindsey Merry L, DeLeon-Pennell Kristine Y

Abstract excerpt

Oral and gum health have long been associated with incidence and outcomes of cardiovascular disease. Periodontal disease increases myocardial infarction (MI) mortality by sevenfold through mechanisms that are not fully understood. The goal of this study was to evaluate whether lipopolysaccharide (LPS) from a periodontal pathogen accelerates inflammation after MI through memory T-cell activation. We compared four...

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Identifiers

PMID: 34597184
DOI: 10.1152/ajpheart.00082.2021
PMCID: PMC8616607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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