Article
Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction?
European heart journal - 14 Mar 2016
Nahrendorf Matthias, Swirski Filip K
Abstract excerpt
Knowledge of macrophages in steady-state and diseased tissue is rapidly expanding, propelled by improved diagnostic capacity to detect and monitor cells in their native environments. In this review, we discuss implications for ischaemic heart disease and examine innate immune cell pathways that increase systemic leucocyte supply after myocardial infarction (MI). Acute MI alters the macrophage phenotype and supply...
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