Article
Peripheral T-cell lymphoma: molecular profiling recognizes subclasses and identifies prognostic markers.
Blood advances - 28 Dec 2021
Rodríguez Marta, Alonso-Alonso Ruth, Tomás-Roca Laura, Rodríguez-Pinilla Socorro M, Manso-Alonso Rebeca, Cereceda Laura, Borregón Jennifer, Villaescusa Teresa, Córdoba Raúl, Sánchez-Beato Margarita, Fernández-Miranda Ismael, Betancor Isabel, Bárcena Carmen, García Juan F, Mollejo Manuela, García-Cosio Mónica, Martin-Acosta Paloma, Climent Fina, Caballero Dolores, de la Fuente Lorena, Mínguez Pablo, Kessler Linda, Scholz Catherine, Gualberto Antonio, Mondéjar Rufino, Piris Miguel A
Abstract excerpt
Peripheral T-cell lymphoma (PTCL) is a clinically aggressive disease, with a poor response to therapy and a low overall survival rate of approximately 30% after 5 years. We have analyzed a series of 105 cases with a diagnosis of PTCL using a customized NanoString platform (NanoString Technologies, Seattle, WA) that includes 208 genes associated with T-cell differentiation, oncogenes and tumor suppressor genes,...
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