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Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

14 Mar 2014

Abstract excerpt

Peripheral T-cell lymphoma (PTCL) encompasses a heterogeneous group of neoplasms with generally poor clinical outcome. Currently 50% of PTCL cases are not classifiable: PTCL-not otherwise specified (NOS). Gene-expression profiles on 372 PTCL cases were analyzed and robust molecular classifiers and oncogenic pathways that reflect the pathobiology of tumor cells and their microenvironment were identified for major...

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PMID: 24632715
DOI: 10.1182/blood-2013-11-536359

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