Article
Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population.
PloS one - 1 Jan 2015
Salo Perttu P, Vaara Satu, Kettunen Johannes, Pirinen Matti, Sarin Antti-Pekka, Huikuri Heikki, Karhunen Pekka J, Eskola Markku, Nikus Kjell, Lokki Marja-Liisa, Ripatti Samuli, Havulinna Aki S, Salomaa Veikko, Palotie Aarno, Nieminen Markku S, Sinisalo Juha, Perola Markus
Abstract excerpt
Myocardial infarction (MI) is divided into either ST elevation MI (STEMI) or non-ST elevation MI (NSTEMI), differing in a number of clinical characteristics. We sought to identify genetic variants conferring risk to NSTEMI or STEMI by conducting a genome-wide association study (GWAS) of MI stratified into NSTEMI and STEMI in a consecutive sample of 1,579 acute MI cases with 1,576 controls. Subsequently, we...
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