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Article

Skin colonization by circulating neoplastic clones in cutaneous T-cell lymphoma

12 Sept 2019

Abstract excerpt

Mycosis fungoides (MF) is a mature T-cell lymphoma currently thought to develop primarily in the skin by a clonal expansion of a transformed, resident memory T cell. However, this concept does not explain the key characteristics of MF, such as the debut with multiple, widespread skin lesions or inability of skin-directed therapies to provide cure. The testable inference of the mature T-cell theory is the...

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PMID: 31515249
DOI: 10.1182/blood.2019002516

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