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Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival

31 Oct 2017

Abstract excerpt

LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs in the fields of vascular biology and neurobiology. How these receptors affect cancer progression in humans remains largely unknown. Herein, we mined provisional databases in The Cancer Genome Atlas (TCGA) to compare expression...

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PMID: 29088295
DOI: 10.1371/journal.pone.0186649

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