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Valosin-Containing Protein (VCP)/p97: A Prognostic Biomarker and Therapeutic Target in Cancer

21 Sept 2021

Abstract excerpt

Valosin-containing protein (VCP)/p97, a member of the AAA+ ATPase family, is a molecular chaperone recruited to the endoplasmic reticulum (ER) membrane by binding to membrane adapters (nuclear protein localization protein 4 (NPL4), p47 and ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1)), where it is involved in ER-associated protein degradation (ERAD). However, VCP/p97 interacts with many...

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PMID: 34576340
DOI: 10.3390/ijms221810177

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Valosin-Containing Protein (VCP)/p97: A Prognostic Biomarker and Therapeutic Target in CancerPMID 34576340Read ↗

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