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The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment

6 Mar 2022

Abstract excerpt

The "totality" of the human exposure is conceived to encompass life-associated endogenous and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only formed in foods by heat processing, but also occur endogenously in the organism as physiological components of energy metabolism, potentially also generated by the human microbiome. To arrive at a comprehensive risk assessment, it is...

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PMID: 35249149
DOI: 10.1007/s00204-022-03242-0

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