Prognostic Impact of Genetic Variants of MECP2 and TIRAP on Clinical Outcomes of Systemic Lupus Erythematosus with and without Nephritis.

doi:10.3390/biom11091378

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Article

Prognostic Impact of Genetic Variants of MECP2 and TIRAP on Clinical Outcomes of Systemic Lupus Erythematosus with and without Nephritis.

Biomolecules - 18 Sept 2021

Tayel Safaa I, Muharram Nashwa M, Fotoh Dina S, Elbarbary Hany S, Abd-Elhafiz Huda I, El-Masry Eman A, Taha Ahmed E, Soliman Shimaa E

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic autoimmune illness with a growing prevalence in many populations. Few studies have examined genetic predisposition to SLE, so we aimed to examine the clinical impact of the genetic polymorphisms MECP2 rs2734647and TIRAP rs8177374 on the outcomes and therapeutic precision of SLE with and without nephritis. This study included 110 SLE patients-divided into 63 with...

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Identifiers

PMID: 34572591
DOI: 10.3390/biom11091378
PMCID: PMC8466489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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