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Article

Transcription factors Krüppel-like factor 4 and paired box 5 regulate the expression of the Grainyhead-like genes.

PloS one - 1 Jan 2021

Kotarba Grzegorz, Taracha-Wisniewska Agnieszka, Miller Michal, Dabrowski Michal, Wilanowski Tomasz

Abstract excerpt

Genes from the Grainyhead-like (GRHL) family code for transcription factors necessary for the development and maintenance of various epithelia. These genes are also very important in the development of many types of cancer. However, little is known about the regulation of expression of GRHL genes. Previously, there were no systematic analyses of the promoters of GRHL genes or transcription factors that bind to...

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PMID: 34570823
DOI: 10.1371/journal.pone.0257977
PMCID: PMC8476022

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