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Article

Potential protective role of Grainyhead-like genes in the development of clear cell renal cell carcinoma.

Molecular carcinogenesis - 1 Nov 2017

Pawlak Magdalena, Kikulska Agnieszka, Wrzesinski Tomasz, Rausch Tobias, Kwias Zbigniew, Wilczynski Bartek, Benes Vladimir, Wesoly Joanna, Wilanowski Tomasz

Abstract excerpt

The involvement of Grainyhead-like (GRHL) transcription factors in various cancers is well documented. However, little is known about their role in clear cell renal cell carcinoma (ccRCC). We discovered that the expression of two of these factors-GRHL1 and GRHL2-are downregulated in ccRCC samples, and their expression is correlated with the expression of VHL gene. This suggests a functional link between the GRHL...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28543713
DOI: 10.1002/mc.22682

Genes

GRHL2
GRHL1
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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