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Article

Polygenic Score for Physical Activity Is Associated with Multiple Common Diseases.

Medicine and science in sports and exercise - 1 Feb 2022

Sillanpää Elina, Palviainen Teemu, Ripatti Samuli, Kujala Urho M, Kaprio Jaakko

Abstract excerpt

INTRODUCTION: Genetic pleiotropy, in which the same genes affect two or more traits, may partially explain the frequently observed associations between high physical activity (PA) and later reduced morbidity or mortality. This study investigated associations between PA polygenic risk scores (PRS) and cardiometabolic diseases among the Finnish population. METHODS: PRS for device-measured overall PA were adapted to...

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Identifiers

PMID: 34559723
DOI: 10.1249/MSS.0000000000002788
PMCID: PMC8754097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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