Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic Risk Scores and Physical Activity.

Medicine and science in sports and exercise - 1 Jul 2020

Kujala Urho M, Palviainen Teemu, Pesonen Paula, Waller Katja, Sillanpää Elina, Niemelä Maisa, Kangas Maarit, Vähä-Ypyä Henri, Sievänen Harri, Korpelainen Raija, Jämsä Timo, Männikkö Minna, Kaprio Jaakko

Abstract excerpt

PURPOSE: Polygenic risk scores (PRS) summarize genome-wide genotype data into a single variable that produces an individual-level risk score for genetic liability. PRS has been used for prediction of chronic diseases and some risk factors. As PRS has been studied less for physical activity (PA), we constructed PRS for PA and studied how much variation in PA can be explained by this PRS in independent population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Exercise

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Finland

Share to Genome-Wide Association Study

Share to Multifactorial Inheritance

Share to Risk Factors

Share to Self Report

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 32049886
DOI: 10.1249/MSS.0000000000002290
PMCID: PMC7292502

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic Risk Scores and Physical Activity.PMID 32049886Read ↗

Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT studySemantic proximity Read ↗

Polygenic Score for Physical Activity Is Associated with Multiple Common Diseases.Semantic proximity Read ↗

Polygenic score for physical activity provides odds for multiple common diseasesSemantic proximity Read ↗

Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT StudySemantic proximity Read ↗

Genetic Liability to Cardiovascular Disease, Physical Activity, and Mortality: Findings from the Finnish Twin Cohort.Semantic proximity Read ↗

Polygenic risk modeling with latent trait-related genetic components.Semantic proximity Read ↗

Current State and Future of Polygenic Risk Scores in Cardiometabolic Disease: A Scoping Review.Semantic proximity Read ↗

Genetic liability for cardiovascular disease, physical activity, and mortality – findings from The Finnish Twin CohortSemantic proximity Read ↗

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK BiobankSemantic proximity Read ↗

From Basic Science to Clinical Application of Polygenic Risk Scores: A Primer.Semantic proximity Read ↗

Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for EpidemiologistsSemantic proximity Read ↗

GWAS identifies 10 loci for objectively-measured physical activity and sleep with causal roles in cardiometabolic disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.