Article

Changes in susceptibility of <i>Plasmodium falciparum</i> to antimalarial drugs in Uganda over time: 2019-2024

2025-01-01

Abstract excerpt

<h4>Background</h4> The treatment and control of malaria in Africa is challenged by drug resistance, including Plasmodium falciparum transporter, folate pathway, and PfK13 mutations that mediate resistance to aminoquinolines, antifolates, and artemisinins, respectively. Characterization of drug susceptibility informs optimal control strategies. <h4>Methods</h4> We characterized ex vivo susceptibilities to nine...

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Literature Corpus work: 93218991-b252-5b78-8b3c-bc9cdbea51f5
DOI: 10.1101/2024.12.31.24319821

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