Article
Expression quantitative trait loci for ETV4 and MEOX1 are associated with adult asthma in Japanese populations.
Scientific reports - 22 Sept 2021
Yatagai Yohei, Oshima Hisayuki, Sakamoto Tohru, Shigemasa Rie, Kitazawa Haruna, Hyodo Kentaro, Masuko Hironori, Iijima Hiroaki, Naito Takashi, Saito Takefumi, Hirota Tomomitsu, Tamari Mayumi, Hizawa Nobuyuki
Abstract excerpt
ETS variant transcription factor 4 (ETV4) is a recently identified transcription factor that regulates gene expression-based biomarkers of asthma and IL6 production in an airway epithelial cell line. Given that ETV4 has not yet been implicated in asthma genetics, we performed genetic association studies of adult asthma in the ETV4 region using two independent Japanese cohorts (a total of 1532 controls and 783...
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