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Article

Association of interleukine-18 polymorphisms with susceptibility to prostate cancer in Iranian population.

Neoplasma - 1 May 2020

Abedinzadeh M, Ghodsian M, Dastgheib S Alireza, Jafari-Nedooshan J, Zare M, Heiranizadeh N, Raee-Ezzabadi A, Neamatzadeh H

Abstract excerpt

Interleukin-18 (IL-18) is a multifunctional cytokine that augments interferon-γ production, promotion of the Th1 immune response and acts as an important immunomediator in the development of some cancers. The current study aimed to analyze the association of the five most common polymorphisms in the IL-18 gene with prostate cancer in the Iranian population. We examined a possible association of IL-18 -137G>C,...

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Identifiers

PMID: 32039628
DOI: 10.4149/neo_2020_190616N513

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