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Article

Identification of candidate regulators of mandibular bone loss in FcγRIIB-/- Mice

21 Sept 2021

Abstract excerpt

Abstract Patients with systemic lupus erythematosus (SLE) have increased inflammatory cytokines, leading to periodontitis and alveolar bone loss. However, the mechanisms driving this phenomenon are still unknown. Here, we have identified novel therapeutic targets for and mediators of lupus-mediated bone loss using RNA-sequencing (RNA-seq) in a FcγRIIB-/- mouse model of lupus associated osteopenia. A total of...

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PMID: 34548536
DOI: 10.1038/s41598-021-98108-3

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