Article
Systematic age‐, organ‐, and diet‐associated ionome remodeling and the development of ionomic aging clocks
23 Apr 2020
Abstract excerpt
Aging involves coordinated yet distinct changes in organs and systems throughout life, including changes in essential trace elements. However, how aging affects tissue element composition (ionome) and how these changes lead to dysfunction and disease remain unclear. Here, we quantified changes in the ionome across eight organs and 16 age groups of mice. This global profiling revealed novel interactions between...
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