Article
Association of Early fMRI Connectivity Alterations With Different Cognitive Phenotypes in Patients With Newly Diagnosed Parkinson Disease.
Neurology - 14 Jan 2025
De Bartolo Maria Ilenia, Ojha Abhineet, Leodori Giorgio, Piervincenzi Claudia, Vivacqua Giorgio, Pietracupa Sara, Costanzo Matteo, D'Antonio Fabrizia, Barbetti Sonia, Margiotta Roberta, Bruno Giuseppe, Conte Antonella, Berardelli Alfredo, Fabbrini Giovanni, Pantano Patrizia, Belvisi Daniele
Abstract excerpt
BACKGROUND AND OBJECTIVES: According to the dual syndrome hypothesis, patients with Parkinson disease (PD) with visuospatial deficits are more likely to progress to dementia, compared with patients with a prevalent dysexecutive syndrome. In this study, we aimed to investigate whether early connectivity changes in the dorsolateral prefrontal cortex (DLPFC) and the precuneus (PCun)-which are critical to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.