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Article

Combining Biomarkers with Genetics In Prodromal/Earliest Phase Parkinson's Disease.

Journal of Parkinson's disease - 1 Jan 2024

Seibler Philip, Streubel-Gallasch Linn, Klein Christine

Abstract excerpt

Family studies have linked several rare genetic variants to hereditary forms of Parkinson's disease (PD). In addition to these monogenic forms, many PD cases are associated with genetic risk factors. Asymptomatic individuals carrying pathogenic variants linked to PD are at risk of developing the disease later in life, thereby providing a unique opportunity for the detection of the earliest pathophysiological and...

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Identifiers

PMID: 39331107
DOI: 10.3233/JPD-240155
PMCID: PMC11492027

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