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Article

Identification of Cancer Driver Modules Based on Graph Clustering from Multiomics Data.

Journal of computational biology : a journal of computational molecular cell biology - 1 Oct 2021

Zhang Wei, Wang Shu-Lin, Liu Yue

Abstract excerpt

A major challenge in cancer genomics is to identify cancer driver genes and modules. Most existing methods to identify cancer driver modules (iCDM) identify groups of genes whose somatic mutational patterns exhibit either mutual exclusivity or high coverage of patient samples, without considering other biological information from multiomics data sets. Here we integrate mutual exclusivity, coverage, and...

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Identifiers

PMID: 34529511
DOI: 10.1089/cmb.2021.0052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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