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Article

Modulation of C-to-T mutation by recombination-independent pairing of closely positioned DNA repeats.

Biophysical journal - 19 Oct 2021

Carlier Florian, Nguyen Tinh-Suong, Mazur Alexey K, Gladyshev Eugene

Abstract excerpt

Repeat-induced point mutation is a genetic process that creates cytosine-to-thymine (C-to-T) transitions in duplicated genomic sequences in fungi. Repeat-induced point mutation detects duplications (irrespective of their origin, specific sequence, coding capacity, and genomic positions) by a recombination-independent mechanism that likely matches intact DNA double helices directly, without relying on the...

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Identifiers

PMID: 34509507
DOI: 10.1016/j.bpj.2021.09.014
PMCID: PMC8553789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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