Article
Integrated Analysis of Transcriptome and Secretome From Umbilical Cord Mesenchymal Stromal Cells Reveal New Mechanisms for the Modulation of Inflammation and Immune Activation.
Frontiers in immunology - 1 Jan 2020
Cruz-Barrera Mónica, Flórez-Zapata Nathalia, Lemus-Diaz Nicolás, Medina Carlos, Galindo Cristian-Camilo, González-Acero Lorena-Xiomara, Correa Luz, Camacho Bernardo, Gruber Jens, Salguero Gustavo
Abstract excerpt
Mesenchymal stromal cells (MSC) have been used in over 800 clinical trials with encouraging results in the field of transplant medicine and chronic inflammatory diseases. Today, Umbilical Cord (UC)-derived MSC are the second leading source used for clinical purposes, mainly due to its easy access and superior immune modulatory effects. Although the underlying molecular mechanisms of immune suppressive activities...
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