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Article

Harnessing miR-16-5p-Loaded Exosomes from Adipose-Derived Stem Cells to Restore Immune Homeostasis in SLE Patients

6 Mar 2025

Abstract excerpt

BACKGROUND: Systemic Lupus Erythematosus (SLE) is an autoimmune disorder marked by an imbalance between pro-inflammatory Th17 cells and regulatory T cells (Tregs), which contributes to chronic inflammation and multi-organ damage, necessitating novel therapeutic strategies. METHODS: This study investigates the potential of adipose-derived stem cell (ADSC) exosomes to modulate the Th17/Treg balance in SLE patients...

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Identifiers

PMID: 40057987
DOI: 10.1016/j.imbio.2025.152885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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