Article
PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals.
F1000Research - 1 Jan 2021
Briggs Peter, Hunter A Louise, Yang Shen-Hsi, Sharrocks Andrew D, Iqbal Mudassar
Abstract excerpt
Many biological studies of transcriptional control mechanisms produce lists of genes and non-coding genomic intervals from corresponding gene expression and epigenomic assays. In higher organisms, such as eukaryotes, genes may be regulated by distal elements, with these elements lying 10s-100s of kilobases away from a gene transcription start site. To gain insight into these distal regulatory mechanisms, it is...
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