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Article

NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.

Cell death & disease - 9 Sept 2021

Hu Yuanbo, Chen Chenbin, Tong Xinya, Chen Sian, Hu Xianjing, Pan Bujian, Sun Xiangwei, Chen Zhiyuan, Shi Xinyu, Hu Yingying, Shen Xian, Xue Xiangyang, Lu Mingdong

Abstract excerpt

The 5-methylcytosine (m5C) RNA methyltransferase NSUN2 is involved in the regulation of cell proliferation and metastasis formation and is upregulated in multiple cancers. However, the biological significance of NSUN2 in gastric cancer (GC) and the modification of NSUN2 itself have not been fully investigated. Here, we analyzed the expression level of NSUN2 in tissue microarrays containing 403 GC tissues by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34504059
DOI: 10.1038/s41419-021-04127-3
PMCID: PMC8429414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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