Article

NSUN2 promotes osteosarcoma metastasis via stabilizing UBE2S mRNA in an m5C-dependent manner

2024-06-04

Abstract excerpt

<title>Abstract</title> <p>5- methylcytosine (m5C) is a prevalent posttranscriptional RNA modification which participates in the initiation and progression of various cancers. NSUN2 is the main RNA methyltransferase import for catalyzing the m5C formation. However, its regulatory role and potential mechanism in osteosarcoma remain unclear. Here, we demonstrated that the NSUN2 expression was markedly upregulated i...

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Literature Corpus work: 18103c66-c2a8-5ac5-a066-2780cb5f1522
DOI: 10.21203/rs.3.rs-4256304/v1

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