Functional polymorphisms of Toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans.

doi:10.1016/j.dld.2012.08.006

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Article

Functional polymorphisms of Toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jan 2013

Pimentel-Nunes Pedro, Teixeira Ana Luísa, Pereira Carina, Gomes Mónica, Brandão Catarina, Rodrigues Catarina, Gonçalves Nádia, Boal-Carvalho Inês, Roncon-Albuquerque Roberto, Moreira-Dias Luís, Leite-Moreira Adelino F, Medeiros Rui, Dinis-Ribeiro Mário

Abstract excerpt

BACKGROUND: Colon carcinogenesis is associated with increased expression levels of Toll-like receptor 2 and Toll-like receptor 4. AIM: To determine in a Caucasian population the role of Toll-like receptor 2 and Toll-like receptor 4 polymorphisms in colorectal cancer development. METHODS: Hospital based multicentre case control study involving 193 colorectal cancer patients and 278 healthy individuals. DNA samples...

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PMID: 22999059
DOI: 10.1016/j.dld.2012.08.006

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TLR2
TLR4
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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