Significant association of MCP1 rs1024611 and CCR2 rs1799864 polymorphisms with colorectal cancer and liver metastases susceptibility and aggressiveness: A case-control study.

doi:10.1016/j.cyto.2023.156193

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Article

Significant association of MCP1 rs1024611 and CCR2 rs1799864 polymorphisms with colorectal cancer and liver metastases susceptibility and aggressiveness: A case-control study.

Cytokine - 1 Jul 2023

Boughriba Rahma, Sahraoui Ghada, Chaar Ines, Weslati Marwa, Ayed Khouloud, Ounissi Donia, Hazgui Mariem, Bouraoui Saadia, Gati Asma

Abstract excerpt

BACKGROUND: The MCP-1/CCR2 axis is one of the major chemokine signaling pathways that play a crucial role in the tumor microenvironment and has been involved in triggering various tumor progression mechanisms, such as increasing the immunosuppressive cells recruitment and promoting tumor cell proliferation and invasiveness. AIM: The current study investigated the association of MCP1 (rs1024611) and CCR2...

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Identifiers

PMID: 37149962
DOI: 10.1016/j.cyto.2023.156193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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