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Article

Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer

1 Sept 2021

Abstract excerpt

High-risk localized prostate cancer (HRLPC) is associated with a substantial risk of recurrence and disease mortality. Recent clinical trials have shown that intensifying anti-androgen therapies administered before prostatectomy can induce pathologic complete responses or minimal residual disease, called exceptional response, although the molecular determinants of these clinical outcomes are largely unknown....

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Identifiers

PMID: 34496240
DOI: 10.1016/j.celrep.2021.109665

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