Article
Dynamics of G6PD activity in patients receiving weekly primaquine for therapy of Plasmodium vivax malaria.
PLoS neglected tropical diseases - 1 Sept 2021
Taylor Walter R J, Kim Saorin, Kheng Sim, Muth Sinoun, Tor Pety, Christophel Eva, Mukaka Mavuto, Kerleguer Alexandra, Luzzatto Lucio, Baird J Kevin, Menard Didier
Abstract excerpt
BACKGROUND: Acute Plasmodium vivax malaria is associated with haemolysis, bone marrow suppression, reticulocytopenia, and post-treatment reticulocytosis leading to haemoglobin recovery. Little is known how malaria affects glucose-6-phosphate dehydrogenase (G6PD) activity and whether changes in activity when patients present may lead qualitative tests, like the fluorescent spot test (FST), to misdiagnose G6PD...
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